Cover image

Cover image: This figure depicts mtDNA deletion detected in the skeletal muscle of a patient with NARP syndrome through in silico prediction of hybridization between nucleotides 5764-5796 (orange) and 16010-16075 (blue) in the presence of wild-type alleles (left) and mutant alleles (right) at positions m.5789 (filled arrow) and position m.5785 (empty arrow). Colored arrowheads indicate deletion breakpoints clustering at the ends of the extended hybridizing stretch. Stylized by Haley McNiff, Digital Multimedia/Podcast Coordinator. See page e660