Article Figures & Data
Figures
- Figure CSMD1 mutations in Parkinson disease
(A) Pedigree structures of 2 families with LOPD and CSMD1 mutations; family A is shown on the left side, whereas family B is shown on the right side. Wt/p.R1962H: heterozygous carriers for the CSMD1 p.R1962H mutation; Wt/p.G2987R: heterozygous carriers for the CSMD1 p.G2987R mutation; Wt/Wt: noncarriers. (B) Sanger chromatogram sequences for both CSMD1 mutations identified in this study are shown at the top, while conservation of both mutations across different species is shown at the bottom. The exact position of the mutations is highlighted with a red arrow. (C) CSMD1 encoding protein structure and the localization of both mutations identified in this study. LOPD = late-onset Parkinson disease.
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