African American exome sequencing identifies potential risk variants at Alzheimer disease loci
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Article Information
- Received September 24, 2016
- Accepted in final form February 10, 2017
- First Published April 7, 2017.
Author Disclosures
- Aurelie N'Songo, PhD,
- Minerva M. Carrasquillo, PhD,
- Xue Wang, PhD,
- Jeremy D. Burgess,
- Thuy Nguyen,
- Yan W. Asmann, PhD,
- Daniel J. Serie,
- Steven G. Younkin, MD, PhD,
- Mariet Allen, PhD,
- Otto Pedraza, PhD,
- Ranjan Duara, MD,
- Maria T. Greig Custo, MD,
- Neill R. Graff-Radford, MD and
- Nilüfer Ertekin-Taner, MD, PhD
- Aurelie N'Songo, PhD,
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- Minerva M. Carrasquillo, PhD,
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(1) Alzheimer?s Association, MNIRGD-13-283007-1, PD/PI, 10/01/2013 ? 09/30/2016 (2) Mayo Clinic, Office of Health Disparities Research Pilot Project, PD/PI, 01/01/2016-12/31/2016
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- Xue Wang, PhD,
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- Jeremy D. Burgess,
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- Thuy Nguyen,
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- Yan W. Asmann, PhD,
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- Daniel J. Serie,
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- Steven G. Younkin, MD, PhD,
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Received funding for a trip from Eisai Pharmaceuticals (2009)
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Received honorarium for speaking engagement from Eisai Pharmaceuticals (2009)
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Funded as the primary investigator by NIH grants AG06656 (2007-2013, AG018023 (2008-2015), R21NS088928 (2014- present), U01AG046139 (2013-present) Funded as the co-investigator by NIH grant AG16574 (2004- 2009), R01NS073512 (2010-present), R01HL111062 (2012- present), U01HL096917 (2013-2015), Florida grant 5AZ08 (2015-present)
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Royalty payments from Mayo for licensing of Tg2576 mouse model of AD (~1998-present)
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- Mariet Allen, PhD,
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NIH R01-1 Subcontract ? Y16 Pilot Project Award, P50AG16574, PI of sub-award, Mayo ADRC.
Mayo Clinic Center for Individualized Medicine
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- Otto Pedraza, PhD,
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NIH NS54722, PI, 2006-2011
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- Ranjan Duara, MD,
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- Maria T. Greig Custo, MD,
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- Neill R. Graff-Radford, MD and
Cytox Consultation
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(1) Alzheimer Disease and Therapy, Editorial Board
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I received royalties for an article in UpToDate
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(1) TauRx FTD multicenter study (2) Lilly multicenter study (3) Biogen multicenter study (4) Axovant multicenter study
(1) NIA P50AG16574 coinvestigator ADRC; (2) NIA U24AG26395 Site PI LOAD study; (3) NIA U01AG24904 Site PI ADNI; (4) NIA R01AG06656 Coinvestigator
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- Nilüfer Ertekin-Taner, MD, PhD
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Editorial Board Member for American Journal of Neurodegenerative Disease.
Human Monoclonal Antibodies Against Amyloid Beta Protein, and Their Use as Therapeutic Agents Application (pending).
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1) National Institutes of Health [R01 AG032990], PI, 2009-2012 2) National Institutes of Health [P50 AG016574], Project PI, 2009-2014 (PI: Ronald Petersen) 3) National Institutes of Health [R01 NS080820], PI, 2013- 2018. 4) National Institutes of Health [U01AG046139], MPI, 2013- 2018 5) National Institutes of Health [RF1AG051504], MPI, 2015-2020. 6) National Institutes of Health [R21AG048101], MPI, 2015-2017
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1) CurePSP, PI, 2012-2014 2) Bright Focus, PI, 2013-2016 3) Florida Health Ed and Ethel Moore Alzheimer?s Disease Research Program Grant, PI, 2015
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- From the Department of Neuroscience (A.N., M.M.C., J.D.B., T.N., S.G.Y., M.A., N.E.-T.), Department of Health Science Research (X.W., Y.W.A., D.J.S.), Department of Psychiatry and Psychology (O.P.), and Department of Neurology (N.R.G.-R., N.E.-T.), Mayo Clinic, Jacksonville; and Wien Center for Alzheimer's Disease and Memory Disorders (R.D., M.T.G.C.), Mount Sinai Medical Center, Miami Beach, FL.
- Correspondence to Dr. Ertekin-Taner: taner.nilufer{at}mayo.edu
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