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August 2016; 2 (4) ArticleOpen Access

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies

Michaela F. George, Farren B.S. Briggs, Xiaorong Shao, Milena A. Gianfrancesco, Ingrid Kockum, Hanne F. Harbo, Elisabeth G. Celius, Steffan D. Bos, Anna Hedström, Ling Shen, Allan Bernstein, Lars Alfredsson, Jan Hillert, Tomas Olsson, Nikolaos A. Patsopoulos, Philip L. De Jager, Annette B. Oturai, Helle B. Søndergaard, Finn Sellebjerg, Per S. Sorensen, Refujia Gomez, Stacy J. Caillier, Bruce A.C. Cree, Jorge R. Oksenberg, Stephen L. Hauser, Sandra D'Alfonso, Maurizio A. Leone, Filippo Martinelli Boneschi, Melissa Sorosina, Ingrid van der Mei, Bruce V. Taylor, Yuan Zhou, Catherine Schaefer, Lisa F. Barcellos
First published August 4, 2016, DOI: https://doi.org/10.1212/NXG.0000000000000087
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Figures

  • Figure 1.
    Figure 1. Density plot of MSSS by cohort

    The density plot represents the frequency distribution of MSSS in each of the 10 cohorts and the total 7,125 individuals with MS. KPNC = Kaiser Permanente Medical Care Plan in the Northern California Region; MS = multiple sclerosis; MSSS = Multiple Sclerosis Severity Score. UCSF = University of California at San Francisco.

  • Figure 2.
    Figure 2. Density plot of age at onset by cohort

    The density plot represents the frequency distribution of age at onset in each of the 10 cohorts and the total 7,125 individuals with MS. KPNC = Kaiser Permanente Medical Care Plan in the Northern California Region; MS = multiple sclerosis; MSSS = Multiple Sclerosis Severity Score. UCSF = University of California at San Francisco.

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